DPCstruct | MC18037

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)296 ± 67 aa
Standard deviation of domain lengths67.30
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score76.47
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.14
Pfam Score96.56
Assigned Pfam label(s) CL0129- PF11708- CL0511

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S6BPJ4 63-325 LSHQSVQQHQKSALDEPVLRGVTSRVAVRYRKNACENCGASTHDVKSCVERPRKKGAKYTNANICPDEYIVENKATGYEAVRDRWSG…
A0A818IFH8 638-1023 HIQLRSVSDQIFLESYARGHADKIATRYRPGACENCGAMTHKRKDCVERPRRLGARFTGTDFAPDEYIQPDINLSWDGKRDRWNGVD…
A0A6A6L2C3 37-216 None
A0A817U1G0 64-470 None
A0A367JD79 59-419 None
H2YSG7 3-251 None
A0A822XSV7 2-205 None
A0A4V3WQS1 40-278 None
A0A835GWH6 71-270 None
A0A1A9X781 6-242 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.