DPCstruct | MC18010

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)499 ± 93 aa
Standard deviation of domain lengths92.76
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score76.16
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.59
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2J7RJK0 3-514 FSSENSELQPCLQVYQVACRFMLVWKKDRDKERFEKLCRYLVSSLESSSIKLSYVGVALNKEYAIAWIAHVKDVLWKCCCYLDELRP…
I7GMF8 1-490 MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFLCRSRLQRDIRREIDDFFKADDPGSTKRSALCVFKIARKLLFVF…
A0A5S6Q0F3 29-590 None
A0A821IQ14 1-439 None
A0A0R3T3Z9 12-472 None
A0A2R9B8S1 3-373 None
A0A7J7P8H9 19-612 None
A8P7F1 8-349 None
A0A7R9FQE5 1-497 None
A0A7J7GMV4 17-570 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.