DPCstruct | MC18009

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)168 ± 30 aa
Standard deviation of domain lengths29.65
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.22
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.31
Pfam Score89.52
Assigned Pfam label(s) PF02177- PF12924

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182VRV7 1-121 MVYPGRDITNIVESSHYQKIGGWCRQGALNAAKCKGAQRWIKPFRCLEGPFQSDALLVPEGCLFDHIHNASRCWPFVRWNQTGAAAC…
I7G8J3 29-189 LAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPY…
A0A7R9NVS0 6-112 None
H9GNC2 23-202 None
A0A183M4U8 20-181 None
A0A7J8AE88 31-193 None
A0A1I7XY11 24-198 None
A0A1I7Y9M6 28-230 None
A0A0S7JU34 22-205 None
A0A4U5MH01 15-204 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.