DPCstruct | MC18008

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)235 ± 14 aa
Standard deviation of domain lengths14.16
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score88.59
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)21.49
Pfam Score100.00
Assigned Pfam label(s) CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O68653 6-240 KEELIKLAYSIRPRENEYKTVLTNLDEYNKLTTNNNENKYLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSP…
A0A3G2FFV3 35-246 LILLDILKTVYVEIISKSSYNSKEANINSIAETFSHAAIAYESGIASNILKSLIFIDELLISIENNFHDIPMYILKKKLLALYQLAF…
A0A6L2ZRZ3 7-239 None
J2WWR7 7-244 None
Q9EXR0 9-230 None
A0A2U8I5V6 3-250 None
E0WUB6 3-225 None
A0A828U171 184-412 None
A0A7U6JX76 169-418 None
A0A2R7TFL7 5-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.