DPCstruct | MC17999

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)91 ± 6 aa
Standard deviation of domain lengths5.99
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.01
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)30.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U1PIP6 6-99 IRVPLHPEHGPLLPAEAMSLLMGVPVEEIRAHSGGEQGTGVMTLPQEWVKAGRRRAKEAHAHGHGGMVEAMTYWAARDHGACLEIEY…
A0A4R8IZQ2 1-102 MIDRRVLLVHEPESGERLMSATAVALLMGVPVAEVEQVWDTSVGPACLPAEWIKAGKRRSAEARAHTGGTSAAIALAYWARKDFGAE…
A0A5Q5BKV4 5-88 None
A0A3N4H0M7 1-88 None
A0A1A2XTG5 1-89 None
A0A239NXE7 1-86 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.