DPCstruct | MC17991

Metacluster Properties and Pfam Annotations

Number of structural domains143
Mean domain length (aa)126 ± 20 aa
Standard deviation of domain lengths20.16
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.47
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)16.82
Pfam Score50.92
Assigned Pfam label(s) CL0127- PF14081- PF14080

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C6DFU7 55-161 DRFIRFGVNVRFFNIEGTEDMLIDTVGMSTLFLPDLQYHFHDMDPNWVVNRAYNVASYILEHDNPIQDGETIDGVADGQMCREIQWK…
A0A1I2IPM5 10-156 FFDEQSEIIEKFGWAVVHVVPTEDDPPDTVPFAYTVGLTGYGFPELTIAGLPPETGHVLLNEVAGRVCDEGLLLRHGHRLRGLLDGQ…
A0A3D9QT54 108-253 None
A0A2W6W3D3 60-202 None
A0A3M2C6K3 55-193 None
B8IQL4 103-251 None
A0A5C7YIK0 17-175 None
A0A2G4GVV4 64-188 None
A0A2L1U572 34-151 None
A0A1D3K8J4 75-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.