DPCstruct | MC17988

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)80 ± 9 aa
Standard deviation of domain lengths8.79
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score94.92
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)44.04
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A150QVP2 107-188 SGGADYHQMRILDVDGDGKDEIADGGYVIDDNGKVLYNLAPQGVVHGDRFHITDLDPARPGLEGWGIQQDNPNGLETYYYDA
A0A2P5HDX9 163-229 APDGHNTRIIDVDGDGRDEVSEIGFTLNSNGTVRYFMGPKGITHGDRFHIAKMDPSRAGLQGYGVQQ
A0A0P0L9A9 27-121 None
A2DPK9 313-399 None
A0A820UM11 30-117 None
B8I5Y4 363-437 None
A0A7C6GCN8 633-719 None
A0A2S8R836 919-1003 None
A0A5P2G2G2 592-680 None
A0A7C4X8F9 63-147 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.