DPCstruct | MC17981

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)142 ± 12 aa
Standard deviation of domain lengths11.91
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.57
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)36.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W1VK63 341-477 HNTFRLWGYYGYEKGFLGYASNKYKQESKQAGHATLGDDYIIQKISDGTFSTLEDWKKAYFNEVVTSAKNGLQAIEVDGTTYSTYDD…
A0A1S9ZBA6 1-138 MAALGYYEGFVPYVSNQFKEEAEAEGVPLSDKYIFDKILGKTYAEFKKEQINERVEKLGKLTPITINYNGKEEVIDSKEKLQELMNK…
A0A139RGU6 292-419 None
A0A0T7K3A1 156-290 None
A0A1S8KNB2 907-1040 None
Q59986 1689-1854 None
A0A3P1VGE7 938-1083 None
A0A139RI03 125-253 None
A0A139QD20 1-128 None
A0A1M4NJ51 1137-1271 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.