DPCstruct | MC17976

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)345 ± 57 aa
Standard deviation of domain lengths56.66
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score70.88
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.32
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)23.46
Pfam Score69.05
Assigned Pfam label(s) PF01422- PF01424

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C4M236 63-390 HFGSCPKCTSLTEKTCYCGKNKVKIPCYIESASCGQICGKPMPCGVHVCKRVCHDGPCTENGQCPYECGKKKPYCTHNCNSKCHGNT…
A8Q2Z3 1-331 MSAVPCSRRNVRCGEPCRALLACGQHICPGACHAEGECPPCNQVCGRPRPVCGHPCERPCHAPEPCSADEPCKAVLARRCACGHREK…
A0A1C7N5K6 217-633 None
A0A1I8FBE0 222-552 None
A0A815P047 1-252 None
A0A194VQM8 57-449 None
A0A6I9YH40 326-642 None
B0EPV2 433-756 None
A0A0M8MYU6 520-943 None
A0A7J6L108 794-1097 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.