DPCstruct | MC17973

Metacluster Properties and Pfam Annotations

Number of structural domains136
Mean domain length (aa)141 ± 26 aa
Standard deviation of domain lengths26.34
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.02
Mean fraction of residues predicted as intrinsically disordered0.94
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)39.23
Pfam Score95.48
Assigned Pfam label(s) CL0352- PF21526

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B1BUY6 20-128 LIGDGANGYTNAQGVGTAGGAGGWLYGDGGTGGTSTRAGVPGGAGGPAGLIGDGGTGGKSVYGGMPGGTGGRGGLLIGDGGTGGASG…
A0A447GCC5 12-137 LTGRSLIGNGANGSPGTGADGTPGGWLLGNGGAGGSGAAGMPGGAGGAAGLLGSGGAGGAGGAGGQLLGNGGGGGEGGAGDGGGGPG…
A0A100ICV4 102-278 None
A0A1X2BEP6 89-238 None
A0A100ID47 1-117 None
A0A2Z5TL81 2-153 None
A0A2Z5TMI9 3-146 None
A0A7I9WIC2 162-360 None
A0A4Z0MXY9 382-516 None
A0A1Q6KKD4 13-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.