DPCstruct | MC17962

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)125 ± 15 aa
Standard deviation of domain lengths14.83
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score91.51
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)20.44
Pfam Score100.00
Assigned Pfam label(s) PF12663

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I0SME2 40-170 EPFQIPTSKDIENLIGTDLYDVWNSLCQRIEKSYEMELLWNRGGKAWTYEYKYRKGGKTLCALYAKEKTLGFMVILGKDERAKFEIQ…
A0A7V6YR62 416-551 IMDKVPTSEDLIALIGKPLFEVWTALCGMIEQKYDMEHLWNNGGKAWEYEYKYRRCGKTLCALYAKENCFGFMVILGKHERTKFETD…
A0A1M4M452 143-278 None
A0A1F3BDU8 2-124 None
A0A7X8MKW7 10-142 None
A0A174ET83 11-137 None
A0A524QS39 11-135 None
I9N1M9 244-382 None
A0A7V3ELG3 59-186 None
A0A1V5Y956 5-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.