DPCstruct | MC17956

Metacluster Properties and Pfam Annotations

Number of structural domains1182
Mean domain length (aa)158 ± 28 aa
Standard deviation of domain lengths28.01
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.08
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.82
Pfam Score99.57
Assigned Pfam label(s) PF13511- CL0020- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378W3D7 74-211 YTLRYISPFKDTVIRHAQNVNVDPAWVYGLIRQESRFVIGAQSRVGAQGLMQVMPATAREIAGKIGMDAAQLYTADGNIRMGTWYMA…
A0A7C1C7R7 27-157 SGSGAVYPDYRRIAEEAARKYGVSPRLAKSVIEVESGWNPGAISRKGAMGLMQLMPETARLYGISDPFDPEENIDAGIRYLKYLIDR…
A0A0G0ZY06 161-373 None
A0A7W1ER23 88-255 None
A0A7W1EKZ4 8-197 None
A0A7Y4Y4H4 7-208 None
A0A7D5UK01 5-143 None
A0A3D5XL25 51-196 None
A0A1A9X6Q4 347-498 None
A0A355I8H8 2-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.