DPCstruct | MC17954

Metacluster Properties and Pfam Annotations

Number of structural domains140
Mean domain length (aa)257 ± 70 aa
Standard deviation of domain lengths70.37
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score88.56
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)20.33
Pfam Score96.25
Assigned Pfam label(s) CL0290- CL0062- CL0063- CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6ETE0 1-153 MGGDITLLNERTEGGEPIADVLVRTSKLHGTTIQGDLIPTLIDEIPMIAVMASQAEGTTIIKDAAELKVKETDRIETVTDNLKAMGC…
A0A7C0YK81 53-320 RCIHFKSPVASAQVKSAVLLAALYAEGETVVEEPRKSRDHTERMLPAIGADIRVEGLRVIVSGGNDISPFEITVPGDFSSAAFFMVA…
A0A7J0G9U8 61-244 None
A0A401FNM0 5-229 None
A0A0G1RQ58 612-926 None
A0A376DLP2 1-190 None
A0A6G3VKG8 42-236 None
A0A1A9UK93 236-549 None
A0A411YK72 227-562 None
W2PKS8 386-712 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.