DPCstruct | MC17945

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)149 ± 15 aa
Standard deviation of domain lengths15.37
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score77.19
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)39.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P4QYE4 136-297 ICSYHFNHDQKNLHNPGFKKTKNTGQSILHRKRCLFCGKLFYFFTRGLGCEKHSWNIIGKNIQVVCNGQVNCSALESYDSVCKRHNE…
A0A2I1FR17 1-142 MKESQKRKCLFCGKLFYFFGRGNGCSKHSQKLLGKNIQVACNRQHTCPALGECNLICKPALEDTKYSCYICSECYELEGGHFHVKPG…
A0A397JP65 1-165 None
A0A397SLJ3 122-278 None
A0A372QT38 142-293 None
A0A2Z6RAN5 3-145 None
A0A397IX34 343-504 None
A0A015KQT9 28-179 None
U9T1T8 161-321 None
A0A2I1H5T2 70-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.