DPCstruct | MC17943

Metacluster Properties and Pfam Annotations

Number of structural domains76
Mean domain length (aa)266 ± 60 aa
Standard deviation of domain lengths59.74
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.63
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)21.57
Pfam Score98.31
Assigned Pfam label(s) CL0123- PF14474

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D3AWK7 613-881 NLCPYCDEPLPFNPTEHIENLKARLEKLSKPAPTTRNPNARDLHWQQAIEFCTLHRAEATIIPLGIQAGYPETMDFKNLDRRLEEGW…
A0A2I1FLE0 24-268 EIQNLTTLSQHCTLPSPQVPHFDEPDFLSNKLNLENDQDKNIECPYCDETLPNPLPSKVSEYLNDISTGKKSACTIVEQYEFCLVHK…
A0A066WLB8 2-205 None
A0A372QTG1 120-354 None
A0A146II59 773-1074 None
A0A0H2R2Q7 341-685 None
I2GW59 32-385 None
A0A0A2V3G1 327-555 None
A0A2N0QEA6 157-423 None
A0A0D2X8B4 4-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.