DPCstruct | MC17882

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)175 ± 14 aa
Standard deviation of domain lengths14.45
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score93.62
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)31.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A350QYC7 169-328 EQWRADTGKKYDTEEVLRLAIQRDPRRETEGGPHHLYGVAYALRRYLDQGGKLSGTWRKAREYLDEYLAISRKHQQEDGAFSAGGFH…
A0A142Y2G6 472-641 IGFSYYLDSNKQWRANDGRIWSISKLIQEELAQPVVGAACGGTHRLMGFSFSVRQRSMQGQPINGQFARADQFVRNYVDYTWTLQNP…
A0A354PEA6 577-736 None
A0A3E0Q7N9 187-393 None
A0A7Y5SMA6 70-248 None
A0A3A0DWA2 159-330 None
A0A7Y2AH27 1-168 None
M5TAJ6 681-872 None
M5SU21 443-619 None
A0A142XUW5 203-362 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.