DPCstruct | MC17854

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)86 ± 10 aa
Standard deviation of domain lengths9.85
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score91.30
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)41.39
Pfam Score100.00
Assigned Pfam label(s) CL0109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6L0R3 53-139 IERKQVYGVTFEQGRNEFKINEELLNNVVTENKEIPQQAKIDLIIALITLKYTQSNSVCYAKNGQAIGIGAGQQSRIHCTRLAGQKA
A0A2B8TRM2 2-78 LLQSADTRGMSLDELKVVSRRAPSEAELRDLLFAWRVAKYVKSNAIVYAKDNRTIGVGAGQMSRVYSARIAGIKAQD
A0A6A5L3U7 822-916 None
A0A6H5HYQ7 725-801 None
A0A5N5QLJ0 387-473 None
A0A1I7Y9I1 252-338 None
A0A485BJ49 108-181 None
A0A377LPX0 1-102 None
A0A377DZ48 1-78 None
A0A2A2KRH5 77-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.