DPCstruct | MC17838

Metacluster Properties and Pfam Annotations

Number of structural domains1264
Mean domain length (aa)187 ± 25 aa
Standard deviation of domain lengths24.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.51
Pfam Score73.69
Assigned Pfam label(s) CL0123- CL0174- PF00199- PF08287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y7L2S1 37-243 None
A0A4D4KE55 678-877 None
A0A1I7EIY8 2-187 None
A0A560J3H1 4-198 None
A0A7R9FTD3 156-357 None
A0A182R0C0 218-433 None
A0A1F9LNA3 5-203 None
A0A377BCC3 19-187 None
A0A4Q9G4H7 1-156 None
A0A024Q8X0 2-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.