DPCstruct | MC17838

Metacluster Properties and Pfam Annotations

Number of structural domains1264
Mean domain length (aa)187 ± 25 aa
Standard deviation of domain lengths24.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.51
Pfam Score73.69
Assigned Pfam label(s) CL0123- CL0174- PF00199- PF08287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M7ZAD1 8-201 None
A0A5E4WQS0 2-182 None
A0A2E4K2W0 7-202 None
A0A5C8BW00 1-165 None
A0A2P8BEN0 8-229 None
A0A6I1JG01 7-186 None
A0A812T349 175-370 None
V5WFY9 2-197 None
A0A1M4W3J0 3-172 None
A0A847K5I6 7-243 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.