DPCstruct | MC17838

Metacluster Properties and Pfam Annotations

Number of structural domains1264
Mean domain length (aa)187 ± 25 aa
Standard deviation of domain lengths24.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.51
Pfam Score73.69
Assigned Pfam label(s) CL0123- CL0174- PF00199- PF08287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1T3NPD6 425-624 None
A0A1S8VYA0 64-257 None
A0A514BMM0 34-241 None
M3A318 67-252 None
M2XQ42 3-169 None
A0A1X0UFH3 2-186 None
A0A5C7NRS0 11-216 None
U1Q3W9 2-232 None
A0A2W4NZ82 52-289 None
W4QJL5 3-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.