DPCstruct | MC17838

Metacluster Properties and Pfam Annotations

Number of structural domains1264
Mean domain length (aa)187 ± 25 aa
Standard deviation of domain lengths24.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.51
Pfam Score73.69
Assigned Pfam label(s) CL0123- CL0174- PF00199- PF08287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q6CCL1 355-566 None
A0A0F6WAD9 68-287 None
A0A0M8KND9 1-162 None
A0A523NEP8 8-203 None
A0A2A6DZF8 5-192 None
A0A2W4ZSK1 8-194 None
A0A7Y3IX21 18-218 None
A0A1L6L6B4 3-165 None
A0A3Q8UV36 3-196 None
A0A1H5F5P3 2-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.