DPCstruct | MC17838

Metacluster Properties and Pfam Annotations

Number of structural domains1264
Mean domain length (aa)187 ± 25 aa
Standard deviation of domain lengths24.74
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.51
Pfam Score73.69
Assigned Pfam label(s) CL0123- CL0174- PF00199- PF08287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1G0JYK1 1-142 MFESLIEFADDSVFGLINKILDQEKDAVDRCGRIIHLLLGFSERNPGITRILLGDALVGENERLRIRVGQFFERIETQFRQVLREAN…
A0A4Q3GB86 20-217 KVVQRAKRGSYDPEGTHTDIMAAGLQLFSEAGFAATTVQAVADRANVTKGAFYHHFESKEDLLRQIHSEYAVEILNSARSVSESGLS…
A0A5C4M714 5-185 None
A0A0X8K8H2 7-203 None
A0A6B2YH61 4-187 None
A0A2E2W4M6 3-192 None
A0A1X1MJ98 5-180 None
A0A449GUS3 2-160 None
A0A258V4W0 2-162 None
A0A1H9HU26 3-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.