DPCstruct | MC17818

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)60 ± 10 aa
Standard deviation of domain lengths10.13
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.73
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)43.04
Pfam Score98.81
Assigned Pfam label(s) PF00643- CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A151NDM3 1-54 MVCEQHGEALKLFCETDQVLMCLICQESRAHRAHPAAPIQEAAQQCKEQLQTQL
A0A402EI69 46-105 CQNMLAVLSIRKGRVCQKHQEPLKLFCKDDEALICVVCDRSKEHRGHETLPLEEASQEYK
A0A4W3GGD1 18-65 None
A0A6J2ASD1 207-276 None
A0A0F8AD76 80-133 None
A0A0G2JTG0 89-150 None
A0A402FLU6 524-577 None
A0A151MYU4 20-85 None
A0A3P9DTN0 168-232 None
S7MM68 700-753 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.