DPCstruct | MC17812

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)134 ± 12 aa
Standard deviation of domain lengths11.90
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score75.09
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)38.86
Pfam Score100.00
Assigned Pfam label(s) CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2IEI3 1-141 MQTVYSSGIYHIGPGHRGRVCITLEPAQLLKGDIMIKCYHKSEATSEREEVFRLQFHTGAVQGYNLVFDKEDMETANKDPRFADYGK…
A0A402ECN6 1-124 LEPALLLKGDVLVKCYHKQLQGAERDVVFQVQLHTCTIHSTQLWFSKDELDEAWRDERFPFEASVEFVFSSSPEKLKGRETYRNHAA…
A0A2G9S330 112-246 None
A0A164RM23 333-475 None
A0A1S3MWR2 102-242 None
A0A3M0J068 57-177 None
F1Q649 268-410 None
A0A5K4FF32 560-668 None
A0A556TSX1 122-243 None
A0A6L5CT82 43-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.