DPCstruct | MC17806

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)117 ± 16 aa
Standard deviation of domain lengths15.53
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.34
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)38.82
Pfam Score100.00
Assigned Pfam label(s) CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4NU76 24-137 YTEVQRVLREEVVNPLRKHGYVRADRVMKLRTLLERLSDVPGLTSEEKDPEEFLNGLVAQLLRAEPFLKLSSGQEAYCYQLFVEKDE…
A0A402EA26 170-265 RYGYVGAENIMHLRKLLRSDSFVTEEKDPEEFLNVLLGEVLATEPLLRIKADNEVLEYNCYQVLVERGSMVHMPTVQQLLEESLLSY…
A0A0N4ZNK9 522-624 None
A0A6P8QSG8 468-566 None
A0A183U7Y3 6-108 None
A0A1L8EU43 257-351 None
A0A3P8QZT6 559-700 None
A0A1A7Z6F6 434-563 None
T1FYR1 108-231 None
A0A485N9D0 398-523 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.