DPCstruct | MC17796

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)126 ± 24 aa
Standard deviation of domain lengths23.82
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.55
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)43.52
Pfam Score93.59
Assigned Pfam label(s) PF12142- CL0205- CL0122

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A830D9B7 66-201 RQMVSNSKTPRLFFGSPYRRGDEPNPGSGSIENIPHGPVHVWTGDSTQPNLENMGNFYSAGRDPIFYGHHSNIDRLWSVWKTLGGRR…
A0A176WHV9 16-127 GVEFKHGDPQNLDINGGGSLEFLPHNSVHRWIGGSTALTTHAPEDPIFYVFHSNLERLWDVWQKLGNSRTDPSTPDWLDAEFLFFDE…
A0A6A3B1Z4 145-246 None
A0A835JP46 169-306 None
A0A4Y7KXC4 11-134 None
B9XQZ3 613-719 None
A0A6G1E4S6 1-102 None
A0A0A0LRV2 155-268 None
A0A396I5T8 252-381 None
A9TFU4 111-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.