DPCstruct | MC17772

Metacluster Properties and Pfam Annotations

Number of structural domains152
Mean domain length (aa)146 ± 23 aa
Standard deviation of domain lengths22.83
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.23
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.85
Pfam Score98.65
Assigned Pfam label(s) PF14449- CL0695

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C2Q553 67-211 None
A0A5C1HZS5 752-901 None
A0A0A8F2B7 443-590 None
A0A3R5ZPH1 103-239 None
A0A0N4VQE4 43-160 None
A0A329CA69 993-1138 None
A0A510JDK4 761-900 None
A0A848JI55 1115-1251 None
A0A3D3MFI8 25-178 None
A0A1B2DEX1 213-388 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.