DPCstruct | MC17756

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)327 ± 54 aa
Standard deviation of domain lengths53.70
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.16
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.02
Pfam Score48.99
Assigned Pfam label(s) PF03223- PF01496

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J7GPC0 214-528 VDSYLTRFVWDEAKYPTFNIPNLRVGTLDSLLSLSDDLAKSNNFMEGVSHKIRRQIEELERVSGGDSGGLTVDGVPVDSYLTRFVWD…
A0A3R7C4L8 533-883 MSEFWIISLPGERNPDEVFERLNASLSKYPGLSSQWKFSIPTDLKVGTLDVLVGLSDELAKLDIYAESITKKVAQYMGDVLEEQRHK…
U6LLC4 30-511 None
A0A3M7M387 3-375 None
A0A226F5A8 12-361 None
A0A2H6K6U7 7-393 None
A0A0C2JFI5 11-354 None
A0A7C6XZQ2 14-243 None
A0A7R9U1L6 29-487 None
A0A182F8F2 435-788 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.