DPCstruct | MC17753

Metacluster Properties and Pfam Annotations

Number of structural domains75
Mean domain length (aa)113 ± 18 aa
Standard deviation of domain lengths17.78
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.42
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)20.44
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U0YRY6 3-112 HGTPEPKPGEPPTKTAKDVRAALDPLPRGDGKSLTRDVRTTPSSNDLREQFRSLPEGAGRGPTPGYPGDQRILSDGTTIGLREKTNS…
A0A1F9G3Y2 256-348 PSITDVLRPGGRLIGEAGTSAQIRILKGGSAEAQALFGQISQGGSVVDETSYPGTLVMLPGGGQVGYRPTSRSGPPTIDVVVEGLGI…
A0A1F3KVU5 155-252 None
G1WKL7 8-117 None
A0A4U8SC61 6-102 None
A0A4U8S662 2-95 None
A0A221VX11 71-195 None
A0A0P8BQS8 188-282 None
A0A7W3W1Z1 345-434 None
A0A520XRF5 492-597 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.