DPCstruct | MC17741

Metacluster Properties and Pfam Annotations

Number of structural domains3187
Mean domain length (aa)308 ± 57 aa
Standard deviation of domain lengths56.94
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.89
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)12.11
Pfam Score73.92
Assigned Pfam label(s) PF10197- CL0261- PF06644- CL0022- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7HGC6 187-548 None
A0A1U7Q319 1-192 None
A0A2P8YJ16 918-1206 None
A0A6S8A2C4 25-413 None
A0A7S3PPY2 193-528 None
A0A4Y2LJD0 17-275 None
A0A6P7FEQ0 19-365 None
A0A6P7FXU7 70-303 None
A0A2N5VA53 129-447 None
V2WRK1 100-431 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.