DPCstruct | MC17741

Metacluster Properties and Pfam Annotations

Number of structural domains3187
Mean domain length (aa)308 ± 57 aa
Standard deviation of domain lengths56.94
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.89
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)12.11
Pfam Score73.92
Assigned Pfam label(s) PF10197- CL0261- PF06644- CL0022- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A521SXU1 2-244 NTGNVLLGAGLAFLAAGLYGFVGLRMGRRVFENPEERLAWNAFRTWWLALAAVTALGALPSVAAVLGVRELWLFLSFTIFNLFGTCL…
A0A3N0YD02 287-628 RNNNFSTMSRDPPLSDQGETIIGVYLLVLGWLSWFGNSIVIFILFKQRSSLQPTDYLTLNLAISDASISVFGYSRGILEIFNVFKDN…
A0A1D2N6D9 343-697 None
A0A1D2N8C9 196-566 None
A0A1D2NJ48 48-341 None
A0A1D2NL70 446-780 None
A0A5C6SW17 18-352 None
A0A5C6SX55 21-364 None
A0A7M3RQM6 568-919 None
A0A1I8IT42 3-357 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.