DPCstruct | MC17725

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)130 ± 29 aa
Standard deviation of domain lengths28.82
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)34.71
Pfam Score91.67
Assigned Pfam label(s) CL0123- PF13651

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K2KHD9 2-99 ADIENELQYYKQHFKNKVVFCNCDDARVSNFFKYFFVHFQELGLKKLISACYVVSGSSQNSKGFYCEYEGKKDWQTTIDELNFFKGD…
A0A7S6MEG3 25-146 KPLNRSLRAAAASKKDEFYTQLPDIEKELKHYTKHFKGKTVLCNCDDPKVSNFFHYFSHNFHKIGLKRLITTCYKNADPDLFSKHQG…
A0A1I5XWD1 63-166 None
A0A5C8FW30 130-237 None
Q50290 1-106 None
A0A1I3KDQ9 1-136 None
A0A1I7IFI2 49-243 None
A0A2S0WY38 4-153 None
A0A7V1ZFH5 2-138 None
A0A6I0VB61 161-268 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.