DPCstruct | MC17719

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)142 ± 21 aa
Standard deviation of domain lengths21.42
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.33
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)47.83
Pfam Score100.00
Assigned Pfam label(s) CL0028

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446RHV7 1-159 MRPDNEVNMALSRMQSGEHPLEALGRLTSNMSTFLKQTNILDKLPEDTLKWKMKLIKRAAQYANCRIQSVTAEVLLLASCDDNLLPS…
A0A452YD93 2-120 LADIIPRDALLWKLKLLKSGAAYANSRLHAVQAEVLFLASGKDNLLPSGEEADRLFKGLKNCRVRYFKENGHTLLLEDGVNLLSVIK…
A0A446UFH4 76-241 None
A0A287RVM4 134-283 None
A0A7J0ELN8 227-366 None
A0A0A9D675 34-169 None
A0A836J9L2 17-158 None
A0A3N7G829 4-141 None
A0A3N7GD01 155-289 None
A0A803KWH5 112-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.