DPCstruct | MC17627

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)367 ± 60 aa
Standard deviation of domain lengths59.63
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score66.25
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)22.01
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S8E7I2 6-336 SLSASSQRERSSTSWADLDLSIIVACVSPIGNWLTGGDHIKNLLLIILLIFYLHQLIEVPWRLYQASRPRKSPGSRTGEPDRVTKLA…
A0A2J8FAZ6 40-479 IRRANTIDESYRRPRSSVTSAAATASGPYDVPRRRDSTLSDYSLGDAGGLFNPKPLGHKPSAEDGSKWTHLPIAFALLPAVGGILFQ…
A0A2S5B719 159-489 None
A0A6A6PXW9 1-459 None
A0A135LLZ6 478-789 None
A0A0C9X9A9 92-468 None
R4X8W2 33-330 None
A0A1D8NKP6 29-443 None
A0A0N0RT15 52-495 None
A0A3N4L3E3 6-372 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.