DPCstruct | MC17578

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)147 ± 20 aa
Standard deviation of domain lengths20.45
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.18
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)31.76
Pfam Score100.00
Assigned Pfam label(s) CL0077

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C7MLQ0 9-143 RSIWTWGYQQNEPTNSERQKHAVELSRKIGIEIIPPKIPLAEELILRPSRIKIPDNLSSYCFTDNYERALHSYGAERELAALGEFPN…
A0A183EK27 28-192 DHILKWNGWGYADSYFEAINPQELAFTGDRYEISGRRLPFLKQYMCETLGIDVDYRTPSVLYEEVSVPTSVDNQQFIDFLLEKGISF…
A0A7S1ZTA0 444-649 None
D2VLW2 10-154 None
A0A7I7LAT5 1-110 None
A0A7P0TA54 79-241 None
K7HD66 10-161 None
A0A4W3JEM4 12-163 None
A0A811KCX9 9-144 None
A0A1I7XJI2 2-117 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.