DPCstruct | MC1753

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)201 ± 32 aa
Standard deviation of domain lengths32.12
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score75.31
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.68
Pfam Score100.00
Assigned Pfam label(s) PF04144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452ZH68 9-194 KNWPPFFPLIHHNISNEIPIHLQKMQYLAFSSFLGIALCLFFNIIATTTAWIKGEGVMVWLLAIIYFISGVPGAYVLWYRPLYNAMR…
A0A087SU44 29-237 NRREAELRRLEQELRAGGAGSLKNWPPYCAFTYHDIRAEIPQPLQGMVRSAYWAYLGLVLCLFFNFVGTAAYLIGVDGGGIAAFLWG…
A0A0G4HWV5 2-218 None
A0A4P1RM67 473-686 None
I1GQK5 340-536 None
A0A5N5ICA9 487-712 None
A0A2K6UCD9 2-174 None
A0A397UDY5 25-200 None
A0A1I8ITC4 2-223 None
H3BBM3 31-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.