DPCstruct | MC175

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)269 ± 36 aa
Standard deviation of domain lengths36.47
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score90.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)18.54
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H3IC53 44-330 HHYASAKEGRELMLSNTEYYENVTQIDIDNRLGKSGGTLDELLEASTAEVKSFNIFEKYIIDRRIANMAKTIARNDYELPYLEEIVF…
A0A6C0B3J1 31-290 MQELFNNPINYEPDHFKRYINNISPKVYFTKTKIKIDSKEEFGSVYLSLLGKVPYYKQAQLDLYTERINKAFRDVNLQNIARTPTEY…
A0A6C0HP16 56-380 None
A0A6C0LMN5 15-228 None
A0A821W1Y1 1-221 None
A0A354FNR9 223-512 None
A0A2E3MSC6 268-567 None
A0A250XN41 489-731 None
D2R1W2 51-332 None
A0A3A5FG74 24-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.