DPCstruct | MC17477

Metacluster Properties and Pfam Annotations

Number of structural domains79
Mean domain length (aa)99 ± 14 aa
Standard deviation of domain lengths13.79
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score88.89
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)47.60
Pfam Score98.37
Assigned Pfam label(s) CL0063- CL0186- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D9XWV4 327-427 DGKKIIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPDEYPTGVYVLPKHLDEKVAALHLDALGVKLTKLRPEQAEYIG…
G7YXQ7 203-296 LAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQLELWNNSDAYSIGVHFLPKKLDEQVAAAHLEHLGVKLTKLTPVQADYLGVPIDGPF…
A0A816WV47 256-348 None
A0A818VQW3 434-529 None
R9P3J3 336-429 None
A0A820FLS7 1-81 None
A0A3Q0JFI5 185-294 None
A0A812ZMG3 607-717 None
A0A0D2MXV8 936-1031 None
A0A182Q529 130-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.