DPCstruct | MC17452

Metacluster Properties and Pfam Annotations

Number of structural domains730
Mean domain length (aa)293 ± 72 aa
Standard deviation of domain lengths71.98
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.27
Pfam Score40.55
Assigned Pfam label(s) CL0210- CL0003- PF00439- PF20722- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J8D6M3 164-460 None
A0A834GUI6 134-490 None
A0A834HEK9 44-379 None
A0A834HGT5 524-930 None
A0A816EH06 18-249 None
K5WQT7 50-444 None
A0A1Y3APC0 278-491 None
D8Q251 52-281 None
D8QD34 250-553 None
A0A813AFA2 135-441 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.