DPCstruct | MC17452

Metacluster Properties and Pfam Annotations

Number of structural domains730
Mean domain length (aa)293 ± 72 aa
Standard deviation of domain lengths71.98
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.27
Pfam Score40.55
Assigned Pfam label(s) CL0210- CL0003- PF00439- PF20722- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I4DC98 192-472 None
A0A6J5V8I3 9-266 None
A0A4Y9Z626 2-474 None
A0A6V7NXQ5 2-361 None
A0A0V0Y9L7 408-743 None
A0A397IVJ8 140-486 None
A0A397IVY8 15-305 None
A0A397J3P6 4-255 None
F8NTV4 221-542 None
A0A6G0Y159 27-221 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.