DPCstruct | MC17452

Metacluster Properties and Pfam Annotations

Number of structural domains730
Mean domain length (aa)293 ± 72 aa
Standard deviation of domain lengths71.98
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.27
Pfam Score40.55
Assigned Pfam label(s) CL0210- CL0003- PF00439- PF20722- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2DBU1 7-241 None
A0A2H5RER4 421-648 None
A0A817XPY9 162-471 None
A0A817YTV1 172-453 None
A0A3Q7XT47 237-549 None
A0A4U5TVP2 780-1074 None
A0A820RV70 118-437 None
A0A0C2Z4G5 443-786 None
A0A0C2ZAT9 53-454 None
A0A0C2ZAT4 89-480 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.