DPCstruct | MC17452

Metacluster Properties and Pfam Annotations

Number of structural domains730
Mean domain length (aa)293 ± 72 aa
Standard deviation of domain lengths71.98
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.27
Pfam Score40.55
Assigned Pfam label(s) CL0210- CL0003- PF00439- PF20722- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A267G558 122-357 RRPRRIDTNLAHFKASEFRLFLLYLGPFFFRKFLPQKYYDHFLHLHFSIYVFCSDVHQTLLPNAHRCIEIFVKEMESLYGEASISYN…
L7LXU5 23-287 LPPNFHKHFCLLVSAIHLLLKDRITREDISDAMGKLSDFVFKMQNLYGEASMTFNVHQLLHLPRSVVELGPLWAHSTFVFESGNGVL…
A0A1D1WC90 2-144 None
A0A2N0QZZ2 3-276 None
A0A5N6PY54 38-462 None
A0A822CXB7 146-416 None
A0A6D2JTG5 55-252 None
A0A6S7FJP3 298-593 None
A0A6S7FWX0 16-234 None
A0A6S7FXA4 350-607 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.