DPCstruct | MC17447

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)91 ± 10 aa
Standard deviation of domain lengths9.57
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.49
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)27.30
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C7PZV9 232-314 PGYLASSTTSVTTGTGSKTWTTQTGLAYSVGARIRVWSTGSGDWMEGVVTAYNTSTGSLTATMDRASGSGTRTDWTINLAGEM
A0A3S3K7N1 66-146 PELIAASTTSLTIGLGSQTWAVPAGKSYEVNMTVRAASDASASNYMEGFVTAVDAVAGSLTVNVTAIGGAGTFADWTLKVK
A0A1M5PXF4 63-169 None
A0A7Y3T6U4 93-177 None
A0A2D6E2N9 57-139 None
A0A516H5U1 31-120 None
A0A2A6NRC3 295-379 None
A0A239GV83 55-165 None
A0A0A1VCF9 273-356 None
A0A7X6FSQ4 14-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.