DPCstruct | MC17435

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)526 ± 74 aa
Standard deviation of domain lengths73.95
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.96
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)23.60
Pfam Score100.00
Assigned Pfam label(s) PF03699

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2WIW1 2-452 AYNLENVERKDFPAGRTLTAQDIADNRATIDNIRLWDWRPLQQTYSQLQEMRLYYEFKNIDIDRYNIDGRYRQVMLAIREMNQDQLS…
A0A7C1RWA2 77-576 QREISWTRITAGLDMFEERSIENFTLSSQAENDTQMISRIRQFDQDFAVQSLAAKIGTTFEGLADSDIVYINGKEYWVAPKTIRLSQ…
A0A7J3LXR1 387-951 None
A0A1C0UVL0 424-994 None
A0A497P060 40-522 None
A0A7C4I562 318-856 None
A0A336P3K8 11-524 None
A0A1D3RPL3 68-605 None
A0A812UG15 574-1157 None
A0A3D2RTH5 3-608 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.