DPCstruct | MC17429

Metacluster Properties and Pfam Annotations

Number of structural domains349
Mean domain length (aa)198 ± 56 aa
Standard deviation of domain lengths56.37
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score83.94
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.03
Pfam Score76.00
Assigned Pfam label(s) PF01548- PF09785- CL0040- CL0198- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378QI50 3-157 None
A0A2V9ZKB3 47-249 None
A0A521NQF0 7-161 None
X0PXV8 18-193 None
A0A3D6BEP1 17-179 None
A0A3D0Y297 2-109 None
A0A7V2ADU9 114-363 None
A0A1H9NBS8 9-219 None
A0A1G7FZD9 19-240 None
A0A5K8A943 23-202 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.