DPCstruct | MC17429

Metacluster Properties and Pfam Annotations

Number of structural domains349
Mean domain length (aa)198 ± 56 aa
Standard deviation of domain lengths56.37
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score83.94
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.03
Pfam Score76.00
Assigned Pfam label(s) PF01548- PF09785- CL0040- CL0198- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y1YPQ5 1-130 None
A0A074KW44 16-215 None
A0A1I3SL56 15-199 None
A0A2E0X2H6 213-437 None
A0A375I5M2 73-290 None
A0A414ENL9 12-136 None
A0A2M8S9M9 171-388 None
A0A0U5I5N6 31-211 None
A0A2V3JK80 17-193 None
A0A4V0NGY7 4-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.