DPCstruct | MC17425

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)144 ± 20 aa
Standard deviation of domain lengths19.57
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.73
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y9ZNW4 106-258 NRLRFKRGMDPLGAGVKGDVLLEGALVQVRVCLVGRGAPDDLAVVYAVGDEEALQWKNAAAQRKKTGNGMAVDNPPDETELSSIVPP…
A0A4V3X9T3 2-152 NKLREKRKMGPLTVRADKLWQSAIVRVSARMCGRGRPEDLAVIYQMDDEEARKWMKAESNRKNGLAAMHENTEDETELSTVAPAQES…
A0A1J8QFP9 308-453 None
A0A5N5QQP4 642-780 None
A0A177TQU9 1075-1242 None
A0A3F2RXZ2 943-1093 None
K3WLE1 737-851 None
A0A183BBE9 4-127 None
A0A5N6KPI2 482-664 None
L1JDB3 601-751 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.