DPCstruct | MC17396

Metacluster Properties and Pfam Annotations

Number of structural domains260
Mean domain length (aa)186 ± 37 aa
Standard deviation of domain lengths36.73
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.24
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.14
Pfam Score99.13
Assigned Pfam label(s) CL0028- CL0281- CL0625- CL0296

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A7REQ6 2-170 KHPLQNRWVLWFFKNDKSKSWAANLRNITSFDTVEDFWGIYNHIQQASRLQPGCDYSLFKDGIEPMWEDKRNKDGGRWLINTNKNQR…
A0A2T9ZAW9 59-250 KDQAEPLSKEQSTSATVNQIDAPTTPNSHPLQYSWTFWYMHREPGQKIVDYEASTIKIGSFFTVEEFWNVYTHTIRPNDMPIILDLH…
A0A1D2MY59 44-240 None
G8BJS0 144-333 None
A0A0W0W1M1 23-171 None
A0A2E0L224 2-134 None
A0A0D2MUE9 116-407 None
A0A1C7NJM3 140-331 None
A0A812QH07 317-556 None
A0A812QFU9 33-281 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.