DPCstruct | MC17380

Metacluster Properties and Pfam Annotations

Number of structural domains149
Mean domain length (aa)109 ± 21 aa
Standard deviation of domain lengths20.65
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.97
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.39
Pfam Score79.61
Assigned Pfam label(s) PF14934- PF10615- CL0336- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N1KL19 17-101 LPFGDDVVEAVLRHMRDDHASDGVVIVRRHGAPGATAALMLGFDALETTWSVTDADGTEGVLTVPWPAPITDRASVRRQVVELFD
A0A2V7F4X6 27-121 WVSAPDYFAAEPDPLVDAAAGVMEHMNRDHADALVAYARFYAGEEANEATMVAVDRLGFKLRLRQGDRLHSVRIAFPREVRTAGESR…
A0A0K2XUG3 3-98 None
A0A2G3D1E0 331-450 None
U2SNY4 19-106 None
A0A7H1N2F9 95-238 None
A0A819TG20 7-115 None
A0A5N6P306 1089-1227 None
R1BTZ2 3-88 None
A0A2A2KJW5 45-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.