DPCstruct | MC17378

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)111 ± 24 aa
Standard deviation of domain lengths23.84
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.17
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)30.49
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V7F3P7 6-112 TRSGMQILYELSAFVSVPEEHVRGGRAFPPPPQAADTENAFPPTVRVLSGSWRPDAAFAAVRYGDHWYWIDDGDLRSKGVFTFLLIL…
A0A286U4K2 206-315 RSIISVLFYLSQNIDIPEEHKKAGLITVTKTQGGEEFNWGETPGGMLFKVRFSKQKPRNAFISVPYRGAWFYIADNDLCSKSTFLLL…
A0A0J7KH79 328-449 None
A0A059V131 1-73 None
A0A177GCW4 26-128 None
A0A445N1M1 5-86 None
A0A2E8Q544 183-291 None
A0A1N6KPC8 272-424 None
A0A7W2YJR8 240-361 None
A0A7C3NR44 35-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.